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A diagnosis of brain metastases or leptomeningeal disease (LMD) from breast cancer is devastating for patients, and presents treatment challenges to the clinical team.
Research and clinical trials are continuously improving our understanding of brain metastases and LMD, also known as central nervous system (CNS) metastases. Both patients and healthcare providers need accurate, up-to-date information about diagnosis and treatment.
Our hub connects you to resources that have been reviewed by medical experts and patient advocates from the CNS Working Group, a global initiative of the Breast International Group (BIG) and the National Clinical Trial Network (NCTN). Many resources can be viewed in your own language using our ReciteMe tool – see how to use it.
Use filters to search for the information you need, or see our recommended content for patients and healthcare providers.

Content on this site is provided as an information resource and is not to be used or relied on for diagnostic or treatment purposes. Medical information provided does not create any patient-physician relationship and should not be used as a substitute for professional diagnosis and treatment. ABC Global Alliance has not reviewed or endorsed detailed information about any clinical trials mentioned in documents or links found on this site – please consult your clinical team to understand if a trial is suitable for you. Treatment guidelines accessed via this hub may be of interest to patients, but please note that they were created for use by clinicians; treatment for ABC should always be personalised for the patient. Always seek the guidance of your doctor or other qualified health professionals with any questions regarding your health or medical condition. Please consult your healthcare provider before making any healthcare decisions or for guidance about a specific medical condition.
This site contains links to resources suitable for sharing with and informing patients diagnosed with brain metastases from breast cancer. In addition, the site offers links to clinical guidelines and treatment information suitable for both specialists and non-breast cancer specialists who would like to be more informed about brain metastases. This is not intended to be comprehensive and may not include the latest publications in the field. Please consult your usual clinical sources for complementary information to be applied in clinical practice.